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Once you click on a specific Lesson or Assignment, a new column will appear with several options. Edit will allow you to change the Lesson Settings or or Assignment Settings. If there are currently active attempts of the Lesson or Assignment, the button Force Grade will appear as well. This forcibly submits these active attempts immediately. For Assignments, you may want to use this option if the deadline has passed and some students forgot to click Submit Assignment meaning their attempt is still in progress.
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